Xeomin

Xeomin® is the latest cosmetic injectable approved by the FDA to treat facial lines and wrinkles.

Xeomin®, like Botox® and Dysport®, are commonly used to treat dynamic wrinkles. Dynamic wrinkles include the forehead lines, fine lines around the eyes, and the furrows between the eyebrows.  Xeomin® works by targeting the wrinkle causing facial muscles in order to eliminate these dynamic lines. Xeomin® can provide a very natural appearing and dramatic improvement in your appearance.

What is Xeomin®?
Xeomin® is a medically derived sub-unit of botulinum toxin type a called incobotulinum toxin a. Xeomin® weakens the muscles into which it is placed, improving the appearance of fine lines and wrinkles.

What is the difference between Xeomin®, Botox® and Dysport®?
On a molecular level, Xeomin® is different from Botox® and Dysport® in that it does not contain any protein additives when packaged. The potential benefit of this is mainly for the rare patient who stopped responding to Botox® treatments because of the development of antibodies to the proteins.

How does Xeomin® work?
Xeomin® works by weakening the muscles of facial expression that insert onto the surface of the skin. Weakening the pull of these muscles on the skin causes the visible wrinkles to flatten out. Over time, cumulative benefits are observed as the skin remodels without the negative influence of the wrinkle-creating facial muscles.

What areas can be treated with Xeomin®?
Xeomin® is used to treat dynamic facial wrinkles. Areas most commonly treated by Xeomin® include crow’s feet (lines around the eyes), worry lines between the eyebrows, and the lines across the forehead.

How long does it take for Xeomin® to work?
The effects of Xeomin® are usually seen within 5 days. It will take up to 10 days to see the final results from the treatment.

How long does Xeomin last?
Xeomin® treatment lasts anywhere from 3-6 months.

Can I switch to Xeomin® if I have used Botox® or Dystport® in the past?
Yes. Since Xeomin® acts in the same physiologic method as both Dysport® and Botox®, the products are interchangeable.

Botox no longer works for me. Will Xeomin®?
This is actually a benefit of Xeomin®. Xeomin® is a “naked” molecule meaning that it does not contain the protein additives that Botox® and Dysport® have. Some patients can develop resistance to the additives within Botox. Xeomin® does not contain any protein additives and therefore will work in these patients.

Before & After Results

See the difference in frown lines before and after treatment with XEOMIN® (incobotulinumtoxinA).

Individual results may vary. All photos are Unretouched. The highest proportion of patients achieved treatment success (at least 2 points improvement in both the investigator and patient ratings) at Day 30. All before and after photos at maximum frown.

Egea Spa Xeomin Before & After - Raquel

Raquel, Age 44
Severe Glabellar Lines

After photo taken 30 days after injection.

Egea Spa Xeomin Before & After - Michelle

Michelle, Age 49
Severe Glabellar Lines

After photo taken 30 days after injection.

Egea Spa Xeomin Before & After - Tracy

Tracy, Age 44
Moderate Glabellar Lines

After photo taken 30 days after injection.

Egea Spa Xeomin Before & After - Cheri

Cheri, Age 53
Moderate Glabellar Lines

After photo taken 14 days after injection.

Egea Spa Xeomin Before & After - Claudia

Claudia, Age 39
Severe Glabellar Lines

After photo taken 14 days after injection.

Egea Spa Xeomin Before & After - Elizabeth

Elizabeth, Age 46
Severe Glabellar Lines

After photo taken 14 days after injection.

Egea Spa Xeomin Before & After - Jill

Jill, Age 45
Severe Glabellar Lines

After photo taken 7 days after injection.

Egea Spa Xeomin Before & After - Julie

Julie, Age 45
Severe Glabellar Lines

After photo taken 7 days after injection.

Egea Spa Xeomin Before & After - Barbara

Barbara, Age 38
Moderate Glabellar Lines

After photo taken 7 days after injection.

Egea Spa Xeomin Before & After - Derek

Derek, Age 41
Moderate Glabellar Lines

After photo taken 7 days after injection.

INDICATION

XEOMIN® (incobotulinumtoxinA) is a prescription medicine that is injected into muscles and used to temporarily improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults.

Important Safety Information
XEOMIN® (incobotulinumtoxinA) may cause serious side effects that can be life threatening. Call your doctor or get medical help right away if you have any of these problems any time (hours to weeks) after treatment with XEOMIN:

  • Problems with swallowing, speaking, or breathing can happen after an injection of XEOMIN if the muscles that you use to breathe and swallow become weak. If these problems are severe, you could die. People with certain breathing problems may need to use muscles in their neck to help them breathe and may be at greater risk for serious breathing problems with XEOMIN.
  • Swallowing problems may last for several months, and during that time you may need a feeding tube to receive food and water. If swallowing problems are severe, food or liquids may go into your lungs. People who already have swallowing or breathing problems before receiving XEOMIN have the highest risk of getting these problems.
  • Spread of toxin effects. In some cases, the effect of botulinum toxin may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism. The symptoms of botulism include: loss of strength and muscle weakness all over the body, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, trouble swallowing

Do not take XEOMIN if you: are allergic to XEOMIN or any of the ingredients in XEOMIN; had an allergic reaction to any other botulinum toxin product such as rimabotulinumtoxinB (Myobloc®), onabotulinumtoxinA (Botox®, Botox® Cosmetic), or abobotulinumtoxinA (Dysport®); have a skin infection at the planned injection site.

Before you take XEOMIN, tell your doctor about all your medical conditions, including if you have a disease that affects your muscles and nerves (such as amyotrophic lateral sclerosis [ALS or Lou Gehrig’s disease], myasthenia gravis or Lambert-Eaton syndrome), as you may be at increased risk of serious side effects including difficulty swallowing or breathing. Tell your doctor if you have: had any side effect from any other botulinum toxin in the past; breathing problems such as asthma or emphysema; a history of swallowing problems or inhaling food or fluid into your lungs (aspiration); bleeding problems; drooping eyelids; plans to have surgery; had surgery on your face. Also tell your doctor if you are pregnant or plan to become pregnant (it is not known if XEOMIN can harm your unborn baby); are breastfeeding or plan to breastfeed (it is not known if XEOMIN passes into breast milk).

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins and herbal products. Using XEOMIN with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received XEOMIN in the past.

Especially tell your doctor if you have received any other botulinum toxin product in the last four months or in the past. Be sure your doctor knows exactly which product you received. The dose of XEOMIN may be different from other botulinum toxin products that you have received. Tell your doctor if you: have recently received an antibiotic by injection; take muscle relaxants; take an allergy or cold medicine; take a sleep medicine; take a blood thinner medicine.

XEOMIN may cause loss of strength or general muscle weakness, blurred vision, or drooping eyelids within hours to weeks of taking XEOMIN. If this happens, do not drive a car, operate machinery, or do other dangerous activities.

XEOMIN may cause other serious side effects including allergic reactions. Symptoms of an allergic reaction to XEOMIN may include: itching, rash, redness, swelling, wheezing, asthma symptoms, or dizziness or feeling faint. Tell your doctor or get medical help right away if you get wheezing or asthma symptoms, or if you get dizzy or faint.

Other side effects of XEOMIN include: dry mouth, discomfort or pain at the injection site, tiredness, headache, neck pain, muscle weakness, and eye problems, including double vision, blurred vision, drooping eyelids, swelling of your eyelids, and dry eyes. Reduced blinking can also occur. Tell your doctor or get medical help right away if you have eye pain or irritation following treatment.

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of XEOMIN. For more information, ask your doctor or pharmacist.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see accompanying XEOMIN full Prescribing Information and Medication Guide.

Botox®, Dysport® and Myobloc® are registered trademarks of their respective owners.

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